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Tae Hyun Kim

  • Assistant Professor of Avian Transgenic Biology
  • Dorothy Foehr Huck and J. Lloyd Huck Early Career Chair,
  • Huck Institutes of Life Sciences
308 Forest Resources Lab
University Park, PA 16802
Work Phone: 814-867-3203

Areas of Expertise

  • Functional Genomics
  • Genome Editing
  • Avian Genetic Engineering

Education

  1. Ph.D. Genetics, University of California, Davis (2019)
  2. M.S. Animal Science, Seoul National University (2007)
  3. B.S. Animal Science, Seoul National University (2005)

* Two Graduate student positions available (Spring/Fall 2021)
* One Postdoc position available

- Please contact Dr. Kim for inquiries

Research Interest

  • Develop in vitro/in vivo avian model system using genome editing tools.
  • Identify candidate genes and pathways associated with economic traits in poultry by applying high-throughput genomic approaches.
  • Understand the genomic networks and molecular/cellular mechanisms of poultry health and reproduction.

Research and Professional Experience

USDA-NIFA-AFRI-EWD postdoctoral fellow, University of California, Davis (2019-20)
USDA-NIFA-AFRI-ELI predoctoral fellow, University of California, Davis (2017-19)
Research associate, WCU Biomodulation, Seoul National University (2011-12)
Research associate, Avicore Biotechnology Institute (2007-11)

Publications

Kim TH, Kern C, Zhou H. Knockout of IRF7 highlights its modulator function of host response against avian influenza virus and the involvement of MAPK and TOR signaling pathways in chicken. Genes. 11(4), 385; doi: 10.3390/genes11040385

Kim TH, Zhou H. Overexpression of chicken IRF7 increased viral replication and programmed cell death to the avian influenza virus infection through TGF-beta/FoxO signaling axis in DF-1. Frontiers in Genetics. 9(415). doi: 10.3389/fgene.2018.00415.

Kim TH, Zhou H. Functional analysis of chicken IRF7 in response to dsRNA analog poly(I:C) by integrating overexpression and knockdown. PLoS One. 10(7). doi:10.1371/journal.pone.0133450

Jang HJ, Lee MO, Kim S, Kim TH, Kim SK, Song G, Womack JE, Han JY. Biallelic expression of the L-arginine:glycine amidinotransferase gene with different methylation status between male and female primordial germ cells in chickens. Poult Sci. 92(3):760-9 

Kim TH, Yun TW, Rengaraj D, Lee SI, Lim SM, Seo HW, Park TS, Han JY. Conserved functional characteristics of the PIWI family members in chicken germ cell lineage. Theriogenology. 78(9):1948-59

Rengaraj D, Lee BR, Choi JW, Lee SI, Seo HW, Kim TH, Choi HJ, Song G, Han JY. Gene pathways and cell cycle-related genes in cultured avian primordial germ cells. Poult Sci. 91(12):3167-77

Rengaraj D, Lee SI, Yoo M, Kim TH, Song G, Han JY. Expression and knockdown analysis of glucose phosphate isomerase in chicken primordial germ cells. Biol Reprod. 87(3):57

Park SH, Kim JN, Park TS, Lee SD, Kim TH, Han BK, Han JY. CpG methylation modulates tissue-specific expression of a transgene in chickens. Theriogenology. 74(5):805-16

Jung JG, Lee YM, Kim JN, Kim TM, Shin JH, Kim TH, Lim JM, Han JY. The reversible developmental unipotency of germ cells in chicken. Reproduction. 139(1):113-9